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Oct 2025 – Present· Researcher (co-first author)

AutoBioLab: Multi-Agent LLM System for Automated Biology Labs

Carnegie Mellon University · Prof. Min Xu & Prof. Rebecca E. Taylor

An LLM agent framework that takes a scientist's intent all the way to executed experiments on liquid-handling robots, with checks before a run and automatic recovery when something goes wrong.

  • Designed a multi-agent framework covering experiment planning, protocol verification and real-time monitoring across multiple liquid handlers.
  • Built pre-execution validation and a hybrid rule + LLM tool-calling recovery agent that repairs failures during a run.
  • Created a 48-task real-experiment planning suite and a 96-scenario fault-injection simulator; benchmarked against 8 LLMs and agent baselines.
  • LLM Agents
  • Laboratory Automation
  • Liquid Handling
Jul 2026 – Sep 2026· Remote Research Assistant (co-author)

OSWorld-Science: Computer-Use Agents on Scientific Software

Northeastern University · Dr. Tianyu Liu & Prof. Wengong Jin

A benchmark that tests whether AI agents can operate real scientific software on a virtual desktop. I built its chemistry domain, the largest and hardest part of the benchmark.

  • Built the chemistry task set, 43 tasks (about 30% of the benchmark), each with an automatic RDKit grader for SMILES, InChIKey and stereochemistry.
  • Connected the tasks to the OSWorld agent harness and evaluated frontier models.
  • Chemistry turned out to be the hardest domain; the best model solved only about 44% of its tasks.
  • Computer-Use Agents
  • Benchmark
  • Cheminformatics
Oct 2025 – Jul 2026· Research Assistant (first author)

CryoPASS: Domain Adaptation for Cryo-ET Segmentation

Carnegie Mellon University · Prof. Min Xu

Segmenting proteins in real cryo-electron tomograms without any real voxel labels, by adapting models trained on simulated data while avoiding the collapse that sparse foregrounds usually cause.

  • Trained 3D protein segmentation models on simulated cryo-ET and adapted them to real tomograms with no real labels.
  • Developed a collapse-free adaptation method (foreground-balance loss, Fourier style alignment, prototype pseudo-labels) that beats the best baseline by 1.8× and reaches 78% of the fully supervised upper bound.
  • Built a benchmark of 9 baselines across backbones and datasets; our method was also the most stable across random seeds.
  • Cryo-ET
  • Domain Adaptation
  • 3D Segmentation
Feb 2023 – May 2023· Undergraduate Researcher (co-first author)

DeepMerip: Denoising Low-Depth MeRIP-seq

Xi'an Jiaotong-Liverpool University · Prof. Zhen Wei

A multi-task CNN that denoises MeRIP-seq signals from low sequencing depth and calls m6A modification peaks.

  • Preprocessed and analyzed HEK293 MeRIP-seq data with ExomePeak2.
  • Co-developed the CNN-based multi-task model for signal denoising and m6A peak calling.
  • Contributed to manuscript writing and data visualization (under review at BMC Bioinformatics).
  • Bioinformatics
  • Deep Learning
  • Epitranscriptomics
Jan 2023 – Oct 2024· Team Leader & Software Developer

ChatParts: LLM Assistant for Synthetic Biology (iGEM 2024)

XJTLU-Software iGEM team · advised by Guoxia Han & Dechang Xu

A retrieval-augmented question-answering system for synthetic biology built on a fine-tuned LLM. Gold Medal in the iGEM AI & Software track.

  • Designed a synthetic biology RAG search framework on top of a fine-tuned LLM.
  • Fine-tuned Llama 3.1 8B on domain data, with embedding-based retrieval, tokenizer optimization and evaluation modules.
  • Built a benchmark for question answering in synthetic biology.
  • iGEM 2024 Gold Medal, AI & Software track.
  • iGEM
  • LLM
  • RAG
  • Synthetic Biology
Jan 2022 – Oct 2022· Website Group Leader

SOLHM: Biofilm Reactor for Sewage Treatment (iGEM 2022)

XJTLU-CHINA iGEM team · advised by Guoxia Han & Dechang Xu

An engineered biofilm reactor for domestic sewage purification. Gold Medal and nominated for Best Environment Project at iGEM 2022.

  • Designed the biofilm reactor instrument for the water purification system.
  • Built biophysical models with GROMACS molecular dynamics, Michaelis–Menten kinetics and the law of mass action.
  • Led the team website and illustrated the full project.
  • iGEM 2022 Gold Medal, nominated for Best Environment Project.
  • iGEM
  • Synthetic Biology
  • Modeling